Model age at adiposity peak and rebound
by INSERM

Being a child with obesity is one of the strongest predictors of obesity in adulthood (Cole et al., 2004). Obesity is generally defined by the body mass index (BMI), which is considered in adults as an indicator of body size. After birth, body mass index (BMI) increases to a peak during the first year of life (adiposity peak; AP) and declines to reach a nadir between age 4 and 6 years, then increases again (Rolland-Cachera et al., 1984; Aris et al., 2018). This BMI increase following the nadir is called the adiposity rebound (AR). An early age at AR (before 5 years in children of European descent) is associated with increased risk of pre-obesity and obesity and cardiometabolic diseases in adulthood (Péneau et al., 2017; Aris et al., 2019). To provide a track to prevent the development of obesity, it is necessary to follow children’s BMI growth curve and better understand the determinants of the kinetics of the BMI curve over age

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Performs data filtering on the data set using a standard pipeline and according to user-defined thresholds.